Renoir is an information-theory-based scoring metric for quantifying the activity between a ligand and its target gene given a specific spatial context. Renoir can also infer spatial communication domains that harbor similar ligand-target activities. Renoir also identifies spatially enriched ligand-target gene sets (pathway activity) and characterizes domain-specific activities between ligands and targets.
NOTE: This repository contains all the code to generate figures/perform benchmarking in the study Charting spatial ligand-target activity using Renoir
Please refer to the Renoir repository for more details
Documentation for Renoir is available at: https://renoir.readthedocs.io/en/latest/
References