v2026.2.2

What's Changed

• Fixes a bug in ClinGen Allele ID generation that was preventing normalized alleles from being paired with their CAID
• Fixes a bug during VEP annotation that was preventing variant recoder results from being parsed and used downstream

Full Changelog: v2026.2.1...v2026.2.2

v2026.2.1

What's Changed

• Added configurable environment variables for Variant Recoder concurrency, batch size, and ClinGen concurrency
• Fixed a bug causing variant translation upserts to fail when run on correlated score sets at the same time
• Increased worker timeout to 3 hours to better support long running VEP jobs

Full Changelog: v2026.2.0...v2026.2.1

v2026.2.0

What's Changed

• Clinvar namespaced variant data export by @bencap in #692
• fix: use NOT EXISTS for superseding score set filter to prevent row m… by @bencap in #707
• fix: filter clinical control options to current mapped variants only by @bencap in #701
• Debug get_score_set_variants_as_csv function. by @EstelleDa in #718
• feat: Support for Multiple Calibrations in VA-Spec Model Exports by @bencap in #658
• Add controlled keywords to score set search filter options. by @EstelleDa in #702
• Job Traceability, Management, and Audibility Overhaul by @bencap in #645
• feat: Target Gene Mapping Table by @bencap in #719

Full Changelog: v2026.1.2...v2026.2.0

v2026.1.2

What's Changed

• fix: Search results returns fewer than expected results by @bencap in #676
• feat: configure database connection pool via environment variables by @bencap in #681
• fix: correct false-positive URN search tests by @bencap in #673
• GET request for multiple score sets by @jstone-dev in #683
• Recently published score sets by @jstone-dev in #686
• fix: duplicate score sets appearing in GET results by @bencap in #690
• feat: add endpoint for user created calibrations by @bencap in #689

Full Changelog: v2026.1.1...v2026.1.2

v2026.1.1

What's Changed

• fix: use na_rep instead of string 'None' for missing score and count data in CSV export by @bencap in #661
• feat: Sortable Collections by @bencap in #660
• chore: add ExCALIBR calibration loading script and remove deprecated PP style calibration script by @bencap in #662
• chore: Replace generic Copilot instruction boilerplate with MaveDB-specific guidance by @bencap in #665
• fix: don't hide published score sets from search when superseded by unpublished versions by @bencap in #667
• Return default alphafold version when parsing or request for XML fails by @davereinhart in #670
• feat: include additional namespaces in Zenodo CSV export by @bencap in #654
• feat: Remove variants from calibration responses, add dedicated variant endpoints by @bencap in #663
• feat: Broaden Score Calibration Permissions Create/Update by @bencap in #666

Full Changelog: v2026.1.0...v2026.1.1

v2026.1.0

What's Changed

• fix: update point label mappings for pillar project assessment levels by @bencap in #585
• feat: add script to count unique variant effect measurements within ACMG-classified ranges by @bencap in #587
• Permissions Module Refactor and Direct Testing by @bencap in #607
• chore: remove passing test logging option from pytest configuration by @bencap in #590
• fix: specify platform as linux/amd64 for dcd-mapping service in docker-compose by @bencap in #594
• fix: mock UTABase fetch in hgvs_genes test for consistent results by @bencap in #595
• Make the updating keywords in the editing experiment accept insensible searching by @EstelleDa in #625
• fix: target gene validation error custom_loc path fix by @davereinhart in #635
• feat: Add external links property to experiments by @bencap in #619
• Categorical Score Calibrations by @bencap in #589
• docs: enhance score set create/patch endpoints with detailed OpenAPI schema for file uploads by @bencap in #630
• feat: add ClinGen namespace to CSV export functionality by @bencap in #626
• fix: Search filters returned all possible options, not just values for which user had permissions by @bencap in #632
• fixed: View model creation fails from non-ORM contexts for models with synthetic properties by @bencap in #631
• fix: Tweaks to ClinGen Service Behavior by @bencap in #633
• Use new layers/gene info format in mapped target metadata by @bencap in #611
• chore: rename Zeiberg calibrations to ExCALIBR across the codebase by @bencap in #648

Full Changelog: v2025.5.0...v2026.1.0

v2025.5.0

What's Changed

• feat: add AlphaFold version proxy endpoint by @davereinhart in #547
• feat: Add Gzip middleware to fastapi, and score set search parameter to optionally skip experiment score set URNs and count by @davereinhart in #548
• feat: Score set search result optimization by @jstone-dev in #525
• feat: Enhance docs for mat view refresh methods and commit their transactions by @bencap in #557
• chore: Remove platform specification from python-base image in Dockerfile by @bencap in #559
• feat: Adds column metadata support and a multipart PATCH endpoint to update score sets and variants by @davereinhart in #546
• fixed: variant count endpoint was returning a count including non-distinct variants by @bencap in #573
• chore: Bump Vulnerable Deps by @bencap in #570
• feat: Modify the function of get_score_set_variants_csv to allow downloading multiple data types together. by @EstelleDa in #541
• feat: Refactor Score Ranges to Score Calibrations and Strengthen Their Data Model by @bencap in #545
• feat: output VRS digest with post mapped HGVS strings by @bencap in #577
• feat: Streaming Endpoints for VA-Spec Annotations by @bencap in #574
• chore: Clean and Standardize OpenAPI Documentation by @bencap in #555
• chore: Add comprehensive instruction files for GitHub Copilot and project guidelines by @bencap in #558
• feat: refactor pillar project calibration loader for use against simplified json by @bencap in #578
• feat: Populate and surface post-mapped HGVS expressions and VEP functional consequence, and surface gnomAD AF by @sallybg in #553

New Contributors

• 🚀 @davereinhart made their first contribution in #547

Full Changelog: v205.4.1...v2025.5.0

v2025.4.1

What's Changed

• Additional Brnich Style Calibrations by @bencap in #519
• Allow ranges to contain a standalone baseline score by @bencap in #527

Full Changelog: v2025.4.0...v205.4.1

v2025.4.0

What's Changed

• Disabled the Gene Ontology code requirement for the "phenotypic assay mechanism" experiment attribute.

Full Changelog: v2025.3.1...v2025.4.0

v2025.3.1

What's Changed

• Rename tax_id to code in Taxonomy by @EstelleDa in #500
• ClinVar control query optimization and control response size reduction by @jstone-dev in #506
• Calibration script and ClinVar control refresh script improvements by @jstone-dev in #507
• Controlled keywords - gene ontology by @EstelleDa in #407
• Release 2025.3.1 by @jstone-dev in #508

Full Changelog: v2025.3.0...v2025.3.1