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@MannLabs

Mann Labs

MannLabs

We develop open-source software for MS-based proteomics, driven by teams at the Max Planck Institute of Biochemistry and the Centre for Proteomics Research (Copenhagen).

Our aim is to provide flexible and future-proof tools for proteomics that span the full data analysis pipeline - from efficient access to raw MS data, through peptide and protein identification and quantification, to biological interpretation and multi-omics integration. We pursue this through:

  • Open science: all software is released under permissive open-source licenses
  • Reproducibility and scientific quality: performant, well-tested, and well-documented methods
  • Accessibility: clear APIs, tutorials, and contribution guidelines
  • Community collaboration: tools designed to be extensible and interoperable

Learn more at https://alphapept.org or reach out on GitHub!

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  1. alphadia alphadia Public

    modular & open DIA search

    Jupyter Notebook 97 9

  2. alphapeptdeep alphapeptdeep Public

    Deep learning framework for proteomics

    Jupyter Notebook 142 23

  3. CKG CKG Public

    Clinical Knowledge Graph (CKG) is a platform with twofold objective: 1) build a graph database with experimental data and data imported from diverse biomedical databases 2) automate knowledge disco…

    Jupyter Notebook 576 121

  4. alphapept alphapept Public

    A modular, python-based framework for mass spectrometry. Powered by nbdev.

    HTML 185 34

  5. alphatims alphatims Public

    An open-source Python package for efficient accession and visualization of Bruker TimsTOF raw data from the Mann Labs at the Max Planck Institute of Biochemistry.

    Python 92 30

  6. alphamap alphamap Public

    An open-source Python package for the visual annotation of proteomics data with sequence specific knowledge.

    Jupyter Notebook 92 21

Repositories

Showing 10 of 56 repositories
  • py-lmd Public

    Read, create and write cutting data for the Leica LMD6 & LMD7 microscope. Build reproducible workflows to calibrate, import SVG files and convert single-cell segmentation masks.

    MannLabs/py-lmd’s past year of commit activity
    Python 13 Apache-2.0 1 2 3 Updated Jan 15, 2026
  • alphadia Public

    modular & open DIA search

    MannLabs/alphadia’s past year of commit activity
    Jupyter Notebook 97 Apache-2.0 9 14 8 Updated Jan 14, 2026
  • alphapepttools Public

    Search- and quantification-engine agnostic biological interpretation of proteomics data

    MannLabs/alphapepttools’s past year of commit activity
    Python 10 Apache-2.0 1 2 15 Updated Jan 14, 2026
  • alphabase Public

    Infrastructure of AlphaX ecosystem

    MannLabs/alphabase’s past year of commit activity
    Python 52 Apache-2.0 13 7 7 Updated Jan 14, 2026
  • scPortrait Public

    scPortrait is a scalable toolkit to generate single-cell representations from raw microscopy images

    MannLabs/scPortrait’s past year of commit activity
    Python 103 Apache-2.0 6 25 4 Updated Jan 12, 2026
  • alphaquant Public

    An open-source Python package for accurate and sensitive peptide and protein quantification.

    MannLabs/alphaquant’s past year of commit activity
    Python 19 Apache-2.0 1 7 2 Updated Jan 12, 2026
  • MannLabs/alphadia-search-rs’s past year of commit activity
    Rust 0 Apache-2.0 0 0 3 Updated Jan 12, 2026
  • alphapept-website Public

    Website for proteomics software tools developed in the MannLabs

    MannLabs/alphapept-website’s past year of commit activity
    HTML 0 0 1 (1 issue needs help) 1 Updated Jan 9, 2026
  • directlfq Public

    Fast and accurate label-free quantification for small and very large numbers of proteomes

    MannLabs/directlfq’s past year of commit activity
    Jupyter Notebook 60 Apache-2.0 7 6 2 Updated Jan 7, 2026
  • research-highlights Public

    MannLabs research highlights in one place

    MannLabs/research-highlights’s past year of commit activity
    HTML 0 CC-BY-SA-4.0 1 0 0 Updated Jan 1, 2026

Most used topics

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