diff --git a/tests/opentelemetry-test-utils/test-requirements-constraints.txt b/tests/opentelemetry-test-utils/test-requirements-constraints.txt
new file mode 100644
index 0000000000..53e085ae7a
--- /dev/null
+++ b/tests/opentelemetry-test-utils/test-requirements-constraints.txt
@@ -0,0 +1,5 @@
+# these are required for weaver integration tests, we're running that only on linux / CPython
+# because of lack of support for gRPC on Windows in some cases.
+opentelemetry-proto ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
+opentelemetry-exporter-otlp-proto-common ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
+opentelemetry-exporter-otlp-proto-grpc ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
diff --git a/tests/opentelemetry-test-utils/test-requirements.txt b/tests/opentelemetry-test-utils/test-requirements.txt
index 6b4dbcec04..246399549e 100644
--- a/tests/opentelemetry-test-utils/test-requirements.txt
+++ b/tests/opentelemetry-test-utils/test-requirements.txt
@@ -15,7 +15,6 @@ zipp==3.19.2
 -e tests/opentelemetry-test-utils
 # these are required for weaver integration tests, we're running that only on linux / CPython
 # because of lack of support for gRPC on Windows in some cases.
-# note: tox does not support PEP 508 markers on `-e` editable installs, so these are installed non-editable
-./opentelemetry-proto ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
-./exporter/opentelemetry-exporter-otlp-proto-common ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
-./exporter/opentelemetry-exporter-otlp-proto-grpc ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
+-e opentelemetry-proto
+-e exporter/opentelemetry-exporter-otlp-proto-common
+-e exporter/opentelemetry-exporter-otlp-proto-grpc
diff --git a/tox.ini b/tox.ini
index d1c5aff8c9..fe7c30ed0a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -122,6 +122,7 @@ deps =
 
   semantic-conventions: -r {toxinidir}/opentelemetry-semantic-conventions/test-requirements.txt
 
+  test-utils: -c {toxinidir}/tests/opentelemetry-test-utils/test-requirements-constraints.txt
   test-utils: -r {toxinidir}/tests/opentelemetry-test-utils/test-requirements.txt
 
   opentelemetry-proto-gen-oldest: -r {toxinidir}/opentelemetry-proto/test-requirements.oldest.txt